Immune Effector Cell Associated Neurotoxicity Syndrome Grade 2

**Semantic type:** Disease or Syndrome

**Definition:** Immune effector cell-associated neurotoxicity syndrome (ICANS) characterized by an immune-effector cell-associated encephalopathy (ICE) tool score of 3, 4, 5, or 6 (for adults and children over 12), or a Cornell Assessment of Pediatric Delirium (CAPD) score of less than 9 (for children 12 and under), and the ability of the affected individual to awaken to voice commands.

**Synonyms:** - ICANS Grade 2 - ICANS Grade 2