NPHS2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NPHS2 wild-type allele is located in the vicinity of 1q25.2 and is approximately 25 kb in length. This allele, which encodes podocin protein, is involved in glomerular function. Mutations in the gene are associated with nephrotic syndrome 2 (steroid-resistant nephrotic syndrome).

**Synonyms:** - NPHS2 Stomatin Family Member, Podocin wt Allele - NPHS2, Podocin Gene - Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) Gene - PDCN - SRN1