KRT12 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KRT12 wild-type allele is located in the vicinity of 17q21.2 and is approximately 6 kb in length. This allele, which encodes keratin, type I cytoskeletal 12 protein, is involved in the structure of intermediate filaments in the anterior corneal epithelium. Mutation of the gene is associated with Meesmann corneal dystrophy 1.

**Synonyms:** - CK-12 - Cytokeratin 12 Gene - K12 - KA12 - Keratin 12 wt Allele - Keratin 12, Type I Gene - Keratin, Type I Cytoskeletal 12 Gene - MECD1 - Meesmann Corneal Dystrophy Gene