Hereditary Paraganglioma-Pheochromocytoma Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** A hereditary cancer syndrome characterized by the development of multiple paragangliomas including pheochromocytomas. It is caused by mutations in SDHA, SDHB, SDHC, SDHD, and SDHAF2 genes.

**Synonyms:** - Familial Paraganglioma-Pheochromocytoma Syndrome - Familial Pheochromocytoma-Paraganglioma Syndrome - Hereditary Pheochromocytoma-Paraganglioma Syndrome