MCCC2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MCCC2 wild-type allele is located in the vicinity of 5q13.2 and is approximately 79 kb in length. This allele, which encodes methylcrotonoyl-CoA carboxylase beta chain, mitochondrial protein, plays a role in leucine and isovaleric acid catabolism. Mutation of the gene is associated with 3-methylcrotonylglycinuria caused by 3-methylcrotonyl-CoA carboxylase 2 deficiency.

**Synonyms:** - 3-Methylcrotonyl-CoA Carboxylase Non-Biotin Containing Subunit Gene - 3-Methylcrotonyl-CoA Carboxylase, Beta Gene - 3-Methylcrotonyl-CoA Carboxylase, Non-Biotin-Containing Subunit Gene - Biotin Carboxylase Gene - MCCB - MCCCbeta - Methylcrotonoyl-CoA Carboxylase 2 (Beta) Gene - Methylcrotonoyl-CoA Carboxylase 2 Gene - Methylcrotonoyl-CoA Carboxylase Beta Gene - Methylcrotonoyl-Coenzyme A Carboxylase 2 (Beta) Gene - Methylcrotonyl-CoA Carboxylase Subunit 2 wt Allele - Non-Biotin Containing Subunit of 3-Methylcrotonyl-CoA Carboxylase Gene