N(6)-Hydroxymethyl-2'-Deoxyadenosine

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide

**Definition:** A formaldehyde metabolite and DNA adduct comprised of the N6-hydroxymethylated form of the purine deoxyadenosine (dAdo). The concentration of N6-hydrxoxymethyl-dAdo in either leukocytes or cells derived from the oral cavity may be directly correlated to levels of formaldehyde exposure, which is correlated with exposure to carcinogenic N-nitrosomethyl compounds.

**Synonyms:** - N(6)-HOCH2-dAdo - N(6)-Hydroxymethyl-dAdo - N-6-Hydroxymethyl-dAdo - N6-HOCH2-dAdo - N6-Hydroxymethyl-2'-Deoxyadenosine - N6-Hydroxymethyl-dAdo - hm6dA