Phosphorylated-STAT1 Y701

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A post-translationally modified form of signal transducer and activator of transcription 1-alpha/beta protein (STAT1) that has been phosphorylated at tyrosine (Y; Tyr) residue 701. Janus kinase (JAK)-mediated phosphorylation of STAT1-Y701 promotes the formation of STAT1 dimers, which translocate into the nucleus and induce STAT1-dependent gene expression.

**Synonyms:** - Phospho-STAT1 Y701 - Phosphorylated-Signal Transducer and Activator of Transcription 1 Y701 - Phosphorylated-Signal Transducer and Activator of Transcription 1-Alpha/Beta Y701 - STAT1 (Phospho-Tyr701) - STAT1 (pY701) - STAT1 Phosphorylated on Tyr701 - STAT1 pY701 - Tyrosine Phosphorylated STAT1 - pY-STAT1