Tyrosine Phosphorylated STAT5

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A post-translationally modified form of signal transducer and activator of transcription 5 (STAT5) that has been phosphorylated at a tyrosine (Y; Tyr) residue. Phosphorylation of STAT5A-Y694 or STAT5B-Y699 promotes STAT5 homodimerization. STAT5A or STAT5B homodimers translocate into the nucleus and induce STAT5-dependent gene expression.

**Synonyms:** - Phosphotyrosine-STAT5 - Tyrosine Phosphorylated-STAT5 - Tyrosine Phosphorylated-Signal Transducer and Activator of Transcription 5 - Tyrosine Phosphorylated-Signal Transducer and Activator of Transcription 5A/5B - pY-STAT5