C190816Level 5
CRADD wt Allele
**Semantic type:** Gene or Genome
**Definition:** Human CRADD wild-type allele is located in the vicinity of 12q22 and is approximately 217 kb in length. This allele, which encodes death domain-containing protein CRADD, is involved in the promotion of apoptosis. Mutation of the gene is associated with autosomal recessive intellectual developmental disorder 34 with variant lissencephaly.
**Synonyms:** - CASP2 and RIPK1 Domain Containing Adaptor with Death Domain wt Allele - MRT34 - RAIDD - RIP-Associated ICH1/CED3-Homologous Protein With Death Domain Gene
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