KCNB1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KCNB1 wild-type allele is located in the vicinity of 20q13.13 and is approximately 191 kb in length. This allele, which encodes potassium voltage-gated channel subfamily B member 1 protein, plays a role in the modulation of repolarization, duration and frequency of repetitive AP firing. Mutation of the gene is associated with developmental and epileptic encephalopathy 26.

**Synonyms:** - DEE26 - DRK1 - Kv2.1 - Potassium Channel, Voltage-Gated, Shab-Related Subfamily, Member 1 Gene - Potassium Voltage-Gated Channel Subfamily B Member 1 wt Allele - Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 Gene