Spastic Paraplegia 56

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal recessive subtype of hereditary spastic paraplegia caused by mutation(s) in the CYP2U1 gene, encoding cytochrome P450 2U1.

**Synonyms:** - Autosomal Recessive Spastic Paraplegia-56 with or without Pseudoxanthoma Elasticum - SPG56