MPDU1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MPDU1 wild-type allele is located in the vicinity of 17p13.1 and is approximately 9 kb in length. This allele, which encodes mannose-P-dolichol utilization defect 1 protein, plays a role in the synthesis of mannose-P-dolichol, which is required for the synthesis of dolichol-linked oligosaccharides, such as glycosylphosphatidylinositols. Mutation of the gene is associated with congenital disorder of glycosylation type 1f.

**Synonyms:** - CDGIF - CDGIf - HBEBP2BPA - LEC35 - Lec35 - Mannose-P-Dolichol Utilization Defect 1 wt Allele - My008 - PP3958 - PQLC5 - SL15 - SLC66A5 - Suppressor of Lec15 Gene - Suppressor of Lec15 and Lec35 Glycosylation Mutation Homolog Gene