SCYL1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SCYL1 wild-type allele is located in the vicinity of 11q13.1 and is approximately 14 kb in length. This allele, which encodes N-terminal kinase-like protein, is involved in regulation of retrograde protein traffic between the Golgi apparatus and the endoplasmic reticulum. One transcript may also be involved in transcriptional regulation. Mutation of the gene is associated with autosomal recessive spinocerebellar ataxia 21, which is also called cholestasis, acute liver failure, and neurodegeneration (CALFAN) syndrome.

**Synonyms:** - CVAK90 - GKLP - HT019 - Likely Ortholog of Mouse N-Terminal Kinase-Like Protein Gene - MGC78454 - N-Terminal Kinase-Like Gene - NKTL - NTKL - P105 - SCAR21 - SCY1 Like Pseudokinase 1 wt Allele - SCY1, S. cerevisiae, Homolog of Gene - SCY1-Like 1 (S. cerevisiae) Gene - SCY1-Like Gene - SCY1-Like, Kinase-Like 1 Gene - TAPK - TEIF - TRAP - Telomerase Transcriptional Elements-Interacting Factor Gene