Tonsoku-Like Protein

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Tonsoku-like protein (1378 aa, ~151 kDa) is encoded by the human TONSL gene. This protein is involved in the regulation of homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks.

**Synonyms:** - I-Kappa-B-Related Protein - IkappaBR - Inhibitor of Kappa B-Related Protein - NF-Kappa-B Inhibitor-Like Protein 2 - Nuclear Factor of Kappa Light Chain Gene Enhancer in B Cells Inhibitor-Like 2 - Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor-Like 2 - TONSL - Tonsoku-Like DNA Repair Protein