Serine Protease Inhibitor Kazal-Type 5

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Serine protease inhibitor Kazal-type 5 (1064 aa, ~121 kDa) is encoded by the human SPINK5 gene. This protein plays a role in the negative regulation of proteolysis that promotes mucosal epithelia formation and keratinocyte terminal differentiation.

**Synonyms:** - LEKTI - Lympho-Epithelial Kazal-Type-Related Inhibitor - Lymphoepithelial Kazal-Type-Related Inhibitor - SPINK5 - Serine Peptidase Inhibitor Kazal Type 5