ALX3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ALX3 wild-type allele is located in the vicinity of 1p13.3 and is approximately 11 kb in length. This allele, which encodes homeobox protein aristaless-like 3 protein, is involved in transcriptional regulation and fetal development. Mutation of the gene is associated with frontonasal dysplasia 1 and preferential methylation of the promoter for the gene may be associated with advanced-stage neuroblastoma.

**Synonyms:** - ALX Homeobox 3 wt Allele - Aristaless-Like Homeobox 3 Gene - FND - FND1 - Frontonasal Dysplasia Gene