BEAN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BEAN1 wild-type allele is located in the vicinity of 16q21 and is approximately 68 kb in length. This allele, which encodes protein BEAN1, may play a role in the regulation of protein ubiquitination. Insertions of over 110 copies of pentanucleotide repeats, including a (TGGAA)n sequence, in intronic regions of this gene (and/or the TK2 gene, which shares an overlapping sequence and is transcribed in the opposite orientation) is associated with spinocerebellar ataxia 31.

**Synonyms:** - BEAN - Brain Expressed Associated with NEDD4 1 wt Allele - Brain-Expressed, Associated with NEDD4 Gene - Brain-Expressed, Associated with NEDD4, 1 Gene - SCA31 - Spinocerebellar Ataxia 31 Gene