Tumor Biology

**Semantic type:** Biomedical Occupation or Discipline

**Definition:** Biological differences between normal and cancer cells. Studies use mechanistic approaches to explore tumor cell biology and tumor progression at the molecular and cellular level, and to examine cell-cell and cell-matrix interactions at the macromolecular level in whole tissues. Included is the study of the pathology and biology of solid tumors and tumor-bearing animals, chimeric, transgenic, and knock-out animals. Research focused on the development of technologies to facilitate these studies is included.