Girentuximab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, monoclonal antibody G250 (mAb G250) may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents. (NCI05)

**Synonyms:** - Chimeric Monoclonal Antibody cG250 - GIRENTUXIMAB - MoAb G250 - Monoclonal Antibody G250 - Rencarex - WX-G250 - cG250