Apamistamab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A murine IgG1 anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity. CD45 antigen, a receptor protein-tyrosine phosphatase essential for T cell development and lymphocyte activation, is expressed on virtually all leukocytes. Apamistamab has specificity for hematopoietic tissues and may be used in targeted immunotherapy.

**Synonyms:** - APAMISTAMAB - Anti-CD45 Monoclonal Antibody BC8 - BC8 - Monoclonal Antibody BC8