NURF

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** The Drosophila NURF complex catalyzes nucleosome sliding. The Nurf301 subunit contains a bromodomain transcription factor domain, a zinc finger binding domain, nuclear localization signals, and motifs associated with rapid protein degradation. The HMGA/HMGI(Y)-like domain of Nurf301 facilitates nucleosome sliding. Nurf301 also interacts with sequence-specific transcription factors, providing a basis for targeted recruitment of the NURF complex to specific genes. (from OMIM 601819, SWISS-PROT Q24572, O77460, Q24368, and NCI)

**Synonyms:** - Nucleosome Remodeling Factor