Childhood Acute Lymphoblastic Leukemia CNS 3 Toronto Guidelines v2

**Semantic type:** Neoplastic Process

**Definition:** Clinical signs of CNS involvement or blasts in CSF and WBC > or = 5/uL CSF and either: RBC < 10/uL CSF or RBC > or = 10/uL CSF and WBC/RBC in CSF > 2x WBC/RBC in blood. (Childhood cancer staging for population registries according to the Toronto Childhood Cancer Stage Guidelines - Version 2. Cancer Council Queensland and Cancer Australia: Brisbane, Australia; 2021.)

**Synonyms:** - Acute lymphoblastic leukemia CNS3 - Childhood Acute Lymphoblastic Leukemia Central Nervous System 3 Toronto Guidelines v2 - Pediatric Acute Lymphoblastic Leukemia CNS 3 Toronto Guidelines v2 - Pediatric Acute Lymphoblastic Leukemia Central Nervous System 3 Toronto Guidelines v2