World Of Taxonomy
C19850Level 6

SWP29

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Tfg3 (TFIIF) is a general stimulatory transcription initiation factor that binds to RNA Polymerase II decreasing its affinity for non-specific DNA. Tfg3 is also a component of the mediator complex and is important for cellular morphogenesis and actin cytoskeletal function. Tfg3 is composed of three subunits and is similar to human ENL and AF-9 proteins. (from SWISS-PROT P35189 and NCI)

**Synonyms:** - ANC1 - TAF30 - TAFII3 - TFG3/TAF30/ANC1 - Tfg3

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