Parkinson Disease 1, Autosomal Dominant

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant subtype of Parkinson disease, caused by mutation(s) in the SNCA gene, encoding alpha-synuclein. Mutation(s) in the SNCA gene are responsible for PARK4 and Lewy body dementia, and have overlapping phenotypes.

**Synonyms:** - PARK1