KMT2A/TET1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation, t(10;11)(q21.3;q23.3), which fuses exon 7, exon 8 or exon 9 of the KMT2A gene with exon 9, exon 10 or exon 12 of the TET1 gene. This chromosomal rearrangement is associated with acute myeloid leukemia with a variant KMT2A rearrangement.

**Synonyms:** - KMT2A-TET1 Fusion Gene - KMT2A::TET1 Fusion Gene - MLL-LCX Fusion Gene - MLL-TET1 Fusion Gene - TET1::KMT2A Fusion Gene