ATXN7L3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ATXN7L3 wild-type allele is located in the vicinity of 17q21.31 and is approximately 8 kb in length. This allele, which encodes ataxin-7-like protein 3, plays a role in the deubiquitination of monoubiquitinated histones. Fusions involving this gene and the UBTF gene resulting from microdeletions within 17q21.31 are associated with B-cell acute lymphoblastic lymphoma and a fusion of this gene and the GPATCH8 gene may be associated with diffuse large B cell lymphoma.

**Synonyms:** - Ataxin 7 Like 3 wt Allele - Ataxin 7-Like 3 Gene - DKFZp761G2113 - SGF11 - SGF11, S. cerevisiae, Homolog of Gene