Anti-IL-11 Monoclonal Antibody 9MW3811

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody directed against interleukin-11 (IL-11), with potential anti-fibrotic and antineoplastic activities. Upon administration, anti-IL-11 monoclonal antibody 9MW3811 targets and binds to IL-11. This prevents the binding of IL-11 to interleukin-11 receptor subunit alpha (IL-11RA), and inhibits IL-11-mediated signaling via the gp130/IL-11RA receptor complex. This may decrease fibrosis and inhibit tumor cell proliferation. IL-11, a member of the IL-6 family of cytokines, is upregulated in some fibro-inflammatory diseases and cancers.

**Synonyms:** - 9MW 3811 - 9MW-3811 - 9MW3811