CRB2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CRB2 wild-type allele is located in the vicinity of 9q33.3 and is approximately 26 kb in length. This allele, which encodes protein crumbs homolog 2 protein, is involved in the formation of a third tissue layer during gastrulation and cell polarity. Mutations in this gene are associated with focal segmental glomerulosclerosis 9 and ventriculomegaly with cystic kidney disease.

**Synonyms:** - Crumbs 2, Cell Polarity Complex Component Gene - Crumbs Cell Polarity Complex Component 2 wt Allele - Crumbs Family Member 2 Gene - Crumbs Homolog 2 (Drosophila) Gene - Crumbs, Drosophila, Homolog of 2 Gene - FLJ16786 - FLJ38464 - FSGS9 - VMCKD