CTH wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CTH wild-type allele is located in the vicinity of 1p31.1 and is approximately 29 kb in length. This allele, which encodes cystathionine gamma-lyase protein, plays a role in cleaving L,L-cystathionine into L-cysteine, ammonia and 2-oxobutanoate. Mutation of the gene is associated with cystathioninuria.

**Synonyms:** - CGL - CSE - Cystathionase (Cystathionine Gamma-Lyase) Gene - Cystathionine Gamma-Lyase wt Allele - Homoserine Deaminase Gene - Homoserine Dehydratase Gene