CUBN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CUBN wild-type allele is located in the vicinity of 10p13 and is approximately 306 kb in length. This allele, which encodes cubilin protein, is involved in binding to intrinsic factor-vitamin B12 complexes. Mutation of the gene is associated with autosomal recessive megaloblastic anemia 1.

**Synonyms:** - Cubilin (Intrinsic Factor-Cobalamin Receptor) Gene - Cubilin wt Allele - IFCR - IGS - IGS1 - MGA1 - gp280