Alizapride Hydrochloride

**Semantic type:** Pharmacologic Substance

**Definition:** The hydrochloride salt form of alizapride, a methoxy-2-benzamide derivative and dopamine 2 (D2) receptor antagonist, with antiemetic activity. Upon administration, alizapride binds to and blocks the D2 receptor in the chemoreceptive trigger zone (CTZ) of the medulla, thereby preventing nausea and vomiting.

**Synonyms:** - ALIZAPRIDE HYDROCHLORIDE - Alizapride HCl - Limican - Litican - Plitican - Vergentan