Dexamethasone Sodium Succinate

**Semantic type:** Pharmacologic Substance

**Definition:** The sodium succinate salt form of dexamethasone, a synthetic adrenal corticosteroid and derivative of hydrocortisone, with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones.

**Synonyms:** - DEXAMETHASONE SODIUM SUCCINATE