WHO Grade 4 Glioma

**Semantic type:** Neoplastic Process

**Definition:** A group of malignant gliomas that includes the following: glioblastoma; diffuse midline glioma; diffuse hemispheric glioma, H3 G34-mutant; astrocytoma, IDH-mutant, grade 4; and diffuse pediatric-type high grade glioma, H3-wildtype and IDH-wildtype.