DGKE wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DGKE wild-type allele is located in the vicinity of 17q22 and is approximately 35 kb in length. This allele, which encodes diacylglycerol kinase epsilon protein, is involved in lipid phosphorylation. Mutation of the gene is associated with nephrotic syndrome type 7 and susceptibility to early-onset atypical hemolytic uremic syndrome 7.

**Synonyms:** - AHUS7 - DAGK5 - DAGK6 - DGK - Diacylglycerol Kinase Epsilon wt Allele - Diacylglycerol Kinase, Epsilon (64kD) Gene - Diacylglycerol Kinase, Epsilon 64kDa Gene - Diacylglycerol Kinase, Epsilon-64kD Gene - NPHS7