DNAI1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DNAI1 wild-type allele is located in the vicinity of 9p13.3 and is approximately 64 kb in length. This allele, which encodes dynein axonemal intermediate chain 1 protein, plays a role in dynein-microtubule interactions and force generation in respiratory cilia. Mutation of the gene is associated with primary ciliary dyskinesia 1.

**Synonyms:** - CILD1 - DIC1 - Dynein Axonemal Intermediate Chain 1 wt Allele - Dynein, Axonemal, Intermediate Chain 1 Gene - Dynein, Axonemal, Intermediate Polypeptide 1 Gene - ICS1 - Immotile Cilia Syndrome 1 Gene - PCD