DSPP wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DSPP wild-type allele is located in the vicinity of 4q22.1 and is approximately 8 kb in length. This allele, which encodes dentin sialophosphoprotein, is involved in dentinogenesis. Mutation of the gene is associated with dentin dysplasia type II, dentinogenesis imperfecta Shields types II and III, and autosomal dominant deafness 39 with dentinogenesis imperfecta.

**Synonyms:** - DFNA39 - DGI1 - DMP3 - DPP - DSP - Deafness, Autosomal Dominant 39 Gene - Dentin Phosphophoryn Gene - Dentin Phosphoprotein Gene - Dentin Sialophosphoprotein wt Allele - Dentin Sialoprotein Gene