DUOX2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DUOX2 wild-type allele is located in the vicinity of 15q21.1 and is approximately 21 kb in length. This allele, which encodes dual oxidase 2 protein, is involved in thyroid hormone synthesis and may be involved in lactoperoxidase activity. Mutations in the gene are associated with dual oxidase 2 deficiency (thyroid dyshormonogenesis 6).

**Synonyms:** - Dual Oxidase 2 wt Allele - Dual Oxidase-Like Domains 2 Gene - Flavoprotein NADPH Oxidase Gene - LNOX2 - NOXEF2 - Nicotinamide Adenine Dinucleotide Phosphate Oxidase Gene - P138-TOX - TDH6 - THOX2