Matuzumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody with antineoplastic activity. Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and inhibiting receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation.

**Synonyms:** - EMD 72000 - EMD 72000 - MATUZUMAB - matuzumab