MYEOV wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MYEOV wild-type allele is located in the vicinity of 11q13.3 and is approximately 48 kb in length. This allele, which encodes myeloma-overexpressed gene protein, may be involved in RNA binding. Concomitant overexpression of this gene and the CCND1 gene is associated with both esophageal squamous cell carcinoma characterized by amplifications at 11q13 and multiple myeloma associated with a chromosomal translocation t(11;14)(q13;q32), which may juxtapose an IGH locus enhancer with the MYEOV gene.

**Synonyms:** - Myeloma Overexpressed (in a Subset of t(11;14) Positive Multiple Myelomas) Gene - Myeloma Overexpressed Gene (in a Subset of t(11;14) Positive Multiple Myelomas) Gene - Myeloma Overexpressed wt Allele - Myeloma-Overexpressed Gene - OCIM - Oncogene in Multiple Myeloma Gene