IGHG2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IGHG2 wild-type allele is located in the vicinity of 14q32.33 and is approximately 5 kb in length. This allele, which encodes immunoglobulin heavy constant gamma 2 protein, plays a role in antigen binding and immunoglobulin receptor binding activities. Mutation of the gene is associated with selective IgG2 deficiency.

**Synonyms:** - Constant Region of Heavy Chain of IgG2 Gene - IgG2 Heavy Chain Constant Region Gene - Immunoglobulin Gamma 2 (Gm Marker) Gene - Immunoglobulin Heavy Constant Gamma 2 (G2m Marker) wt Allele - Immunoglobulin Heavy Constant Gamma 2 (Gm Marker) Gene