IGHG3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IGHG3 wild-type allele is located in the vicinity of 14q32.33 and is approximately 7 kb in length. This allele, which encodes immunoglobulin heavy constant gamma 3 protein, is involved in antibody-mediated immunity. Mutations that cause deletions in the region the N-terminal part of the encoded protein are associated with heavy chain disease.

**Synonyms:** - C Gamma 3 Gene - Constant Region of Heavy Chain of IgG3 Gene - IgG3 - Immunoglobulin Gamma 3 (Gm Marker) Gene - Immunoglobulin Heavy Constant Gamma 3 (G3m Marker) wt Allele - Immunoglobulin Heavy Constant Gamma 3 (Gm Marker) Gene - Secreted-Type Ig Gamma Heavy-Chain Gene