MI-2 Antigens

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** Antigens derived from certain helicases in the nucleosome remodeling-deacetylase complex (NuRD) involved in transcription regulation that may be comprised of (but not limited to) two isoforms Mi-2 alpha and Mi-2 beta. They can be considered as autoantigens and are commonly associated with systemic autoimmune myopathy dermatomyositis.

**Synonyms:** - Dermatomyositis Autoantigen Mi-2 - MI-2 ANTIGENS - Major Dermatomyositis-specific Mi-2 Autoantigen