ACF complex

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** The Drosophila gene Acf1 encodes ATP-dependent chromatin assembly factor large subunit, a component of the chromatin assembly complex involved in chromatin assembly/disassembly. Acf1 contains a PHD-finger and is able to modulate the internucleosomal spacing of chromatin by an ATP-dependent mechanism. Similar sequences have been identified in Caenorhabditis elegans, Homo sapiens, Mus musculus, and Saccharomyces cerevisiae. (from FlyBase 0027620 and NCI)

**Synonyms:** - ACF