Arterial Calcification due to Deficiency of CD73

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal recessive condition caused by mutation(s) in the NT5E gene, encoding 5'-nucleotidase. Deficiency in this enzyme (also know as CD73 antigen) results in arterial calcification of the lower extremities, and the joints affecting the hands and feet.

**Synonyms:** - ACDC - CALJA