HADHA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HADHA wild-type allele is located in the vicinity of 2p23.3 and is approximately 54 kb in length. This allele, which encodes trifunctional enzyme subunit alpha, mitochondrial protein, plays a role in the final steps of the mitochondrial beta-oxidation pathway. Mutation of the gene is associated with long-chain 3-hydroxyl-CoA dehydrogenase (LCHAD) deficiency and mitochondrial trifunctional protein deficiency 1.

**Synonyms:** - 3-Ketoacyl-Coenzyme A (CoA) Thiolase, Alpha Subunit Gene - 3-Oxoacyl-CoA Thiolase Gene - ECHA - GBP - Gastrin-Binding Protein Gene - HADH - Hydroxyacyl-CoA Dehydrogenase Trifunctional Multienzyme Complex Subunit Alpha wt Allele - Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/Enoyl-CoA Hydratase (Trifunctional Protein), Alpha Subunit Gene - Hydroxyacyl-CoA Dehydrogenase/3-Ketoacyl-CoA Thiolase/Enoyl-CoA Hydratase, Alpha Subunit Gene - Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/Enoyl-Coenzyme A Hydratase (Trifunctional Protein), Alpha Subunit Gene - LCEH - LCHAD - Long-Chain 2-Enoyl-CoA Hydratase Gene - Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase Gene - MTPA - Mitochondrial Long-Chain 2-Enoyl-Coenzyme A (CoA) Hydratase, Alpha Subunit Gene - Mitochondrial Long-Chain L-3-Hydroxyacyl-Coenzyme A (CoA) Dehydrogenase, Alpha Subunit Gene - Mitochondrial Trifunctional Enzyme, Alpha Subunit Gene - Mitochondrial Trifunctional Protein, Alpha Subunit Gene - TP-ALPHA - Trifunctional Enzyme Subunit Alpha, Mitochondrial Gene - Trifunctional Protein, Alpha Subunit Gene