HNF4A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HNF4A wild-type allele is located in the vicinity of 20q13.12 and is approximately 79 kb in length. This allele, which encodes hepatocyte nuclear factor 4-alpha protein, is involved in transcriptional regulation of hepatic genes. Mutation of the gene is associated with non-insulin dependent diabetes mellitus, maturity-onset diabetes of the young (MODY) 1, and Fanconi renotubular syndrome 4 with MODY.

**Synonyms:** - FRTS4 - HNF4 - HNF4-Alpha - HNF4a7 - HNF4a8 - HNF4a9 - HNF4alpha - Hepatic Nuclear Factor 4 Alpha Gene - Hepatocyte Nuclear Factor 4 Alpha wt Allele - MODY - MODY1 - NR2A1 - TCF-14 - TCF14 - Transcription Factor 14, Hepatic Nuclear Factor Gene