HSD11B2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HSD11B2 wild-type allele is located in the vicinity of 16q22.1 and is approximately 8 kb in length. This allele, which encodes 11-beta-hydroxysteroid dehydrogenase type 2 protein, is involved in the metabolism of corticosteroids. Mutations in this gene are associated with 11-beta-hydroxysteroid dehydrogenase type 2 deficiency, which results in apparent mineralocorticoid excess syndrome.

**Synonyms:** - 11-Beta-HSD2 Gene - 11-Beta-Hydroxysteroid Dehydrogenase, Type II Gene - AME - AME1 - HSD11, Kidney and Placental Type Gene - HSD11, Type II Gene - HSD11K - HSD2 - Hydroxysteroid (11-Beta) Dehydrogenase 2 Gene - Hydroxysteroid 11-Beta Dehydrogenase 2 wt Allele - SDR9C3 - Short Chain Dehydrogenase/Reductase Family 9C, Member Gene