Toxicogenomics

**Semantic type:** Biomedical Occupation or Discipline

**Definition:** Toxicogenomics is a new scientific field that elucidates how the entire genome is involved in biological responses of organisms exposed to environmental toxicants/stressors. Toxicogenomics combines information from studies of genomic-scale mRNA profiling (by microarray analysis), cell-wide or tissue-wide protein profiling (proteomics), genetic susceptibility, and computational models to understand the roles of gene-environment interactions in disease. (from National Center for Toxicogenomics homepage)