IL36RN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IL36RN wild-type allele is located in the vicinity of 2q14.1 and is approximately 7 kb in length. This allele, which encodes interleukin-36 receptor antagonist protein, is involved in binding to interleukin-1 receptor-like 2, which inhibits interleukin-36 binding and signaling. Mutations in the gene are associated with pustular psoriasis 14 (deficiency of IL36RN).

**Synonyms:** - FIL1 - FIL1(DELTA) - FIL1-DELTA - FIL1D - Family of Interleukin 1-Delta Gene - IL-1 Related Protein Gene - IL-1F5 (IL-1HY1, FIL1-Delta, IL-1RP3, IL-1L1, IL-1-Delta) Gene - IL-36Ra - IL1F5 - IL1F5 (Canonical Product IL-1F5a) Gene - IL1HY1 - IL1L1 - IL1RP3 - IL36RA - Interleukin 1 Family, Member 5 (Delta) Gene - Interleukin 1 Family, Member 5 Gene - Interleukin 1 Receptor Antagonist Homolog 1 Gene - Interleukin 36 Receptor Antagonist wt Allele - MGC29840 - PSORP - PSORS14