INF2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human INF2 wild-type allele is located in the vicinity of 14q32.33 and is approximately 41 kb in length. This allele, which encodes inverted formin-2 protein, plays a role in cytoskeletal actin filament remodeling. Mutation of the gene is associated with focal segmental glomerulosclerosis 5 and dominant intermediate Charcot-Marie-Tooth disease E.

**Synonyms:** - C14orf151 - C14orf173 - CMTDIE - Chromosome 14 Open Reading Frame 151 Gene - Chromosome 14 Open Reading Frame 173 Gene - FSGS5 - Formin, Inverted, 2 Gene - HBeAg-Binding Protein 2 Binding Protein C Gene - Inverted Formin 2 wt Allele - Inverted Formin, FH2 and WH2 Domain Containing Gene - MGC13251 - pp9484